The European Commission is to prohibit the use of 31 carcinogenic, mutagenic or toxic for reproduction (CMR) substances in cosmetic products. The Commission notified WTO of the amendments on November 17, 2022.
The CMRs that are affected include:
- ammonium bromide;
- benzophenone;
- acetamiprid;
- 2,4,6-tri-tert-butylphenol;
- dibutyltin di(acetate); and
- 2-ethylhexanoic acid and its salts, with the exception of those specified in Annex VI to the cosmetic products Regulation.
These substances were added to Annex II of the Regulation (EC) No 1223/2009 and the ban on their use in cosmetics will apply from December 1, 2023.
Previously on May 23, 2022, these 31 substances were added to Annex VI of the Regulation on the classification, labelling and packaging of substances and mixtures (CLP) during the 18th adaptation to technical progress (ATP)
Annex II is amended as follows:
1. Entry 1024 of Annex II is replaced by the following:
Chemical name/INN | CAS number |
2-ethylhexanoic acid and its salts with the exception of those specified elsewhere in Annex VI to Regulation (EC) No 1272/2008 | 149-57-5/- |
2. The following entries are added:
Chemical name/INN | CAS number | The Regulatory list in China |
Ammonium bromide | 12124-97-9 | Inventory of Existing Chemical Substances in China (IECSC) |
Dibutyltin bis(2-ethylhexanoate) | 2781-10-4 | IECSC |
Dibutyltin di(acetate) | 1067-33-0 | |
Tellurium dioxide | 7446-07-3 | IECSC |
Barium diboron tetraoxide | 13701-59-2 | IECSC |
2,2-dimethylpropan-1-ol,tribromo derivative;3-bromo-2,2-bis(bromomethyl) propan-1-ol | 36483-57-5/ 1522-92-5 | IECSC |
2,4,6-tri-tert-butylphenol | 732-26-3 | IECSC |
4,4’-sulphonyldiphenol; bisphenol S | 80-09-1 | IECSC |
Benzophenone | 119-61-9 | Inventory of Existing Cosmetic Ingredients in China (IECIC 2021) |
Quinoclamine(ISO); 2-amino-3-chloro-1,4-naphthoquinone | 2797-51-5 | |
Perfluoroheptanoic acid; tridecafluoroheptanoic acid | 375-85-9 | |
Methyl N-(isopropoxycarbonyl)-L-valyl- (3RS)-3-(4-chlorophenyl)-β-alaninate; valifenalate | 283159-90-0 | |
6-[C12-18-alkyl-(branched,unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid, sodium and tris(2-hydroxyethyl)ammonium salts | / | |
6-[(C10-C13)-alkyl-(branched,unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid | 2156592-54-8 | |
6-[C12-18-alkyl-(branched,unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid | / | |
Theophylline;1,3-dimethyl-3,7-dihydro-1Hpurine-2,6-dione | 58-55-9 | IECIC 2021 |
1,3,5-triazine-2,4,6-triamine; melamine | 108-78-1 | IECSC |
Fluopicolide (ISO); 2,6-dichloro-N-[3-chloro5-(trifluoromethyl)-2- pyridylmethyl]benzamide | 239110-15-7 | |
N-(2-nitrophenyl)phosphoric triamide | 874819-71-3 | |
N-(5-chloro-2-isopropylbenzyl)-Ncyclopropyl-3-(difluoromethyl)-5-fluoro-1- methyl-1H-pyrazole-4-carboxamide; isoflucypram | 1255734-28-1 | |
Reaction mass of 3-(difluoromethyl)-1-methylN-[(1RS,4SR,9RS)-1,2,3,4-tetrahydro-9- isopropyl-1,4-methanonaphthalen-5- yl]pyrazole-4-carboxamide and 3- (difluoromethyl)-1-methyl-N-[(1RS,4SR,9SR)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4- carboxamide [>78% syn isomers <15% anti isomers relative content]; isopyrazam | 881685-58-1 | |
Margosa, ext. [from the kernels of Azadirachta indica extracted with water and further processed with organic solvents] | 84696-25-3 | IECIC 2021 |
Cumene | 98-82-8 | IECSC |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3- propanediyl diacrylate; 2,2- bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate; | 15625-89-5 | IECIC 2021 |
Pentapotassium 2,2’,2’’,2’’’,2’’’’-(ethane-1,2-diylnitrilo)pentaacetate | 7216-95-7 | IECSC |
Ncarboxymethyliminobis(ethylenenitrilo)tetra(a cetic acid); Pentetic Acid (INCI) | 67-43-6 | IECIC 2021 |
Pentasodium(carboxylatomethyl)iminobis(ethylenenitrilo)te traacetate; Pentasodium Pentetate (INCI) | 140-01-2 | IECIC 2021 |
Acetamiprid(ISO);(1E)-N-[(6-chloropyridin3-yl)methyl]-N'-cyano-Nmethylethanimidamide;(E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1- methylacetamidine | 135410-20-7/ 160430-64-8 | IECSC |
Pendimethalin(ISO);N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene | 40487-42-1 | IECSC |
Bentazone (ISO); 3-isopropyl-2,1,3- benzothiadiazine-4-one-2,2-dioxide | 25057-89-0 | IECSC |
Substances including Benzophenone, Theophylline, Melia Azadirachta Seed Extract, Trimethylolpropane Triacrylate, Pentetic Acid, Pentasodium Pentetate are also listed in the Inventory of Existing Cosmetic Ingredients in China (IECIC 2021), if you would like to know more info about these substances or whether your substances are listed in the IECIC, please search our free cosmetic inventory search system – China CosIng 20.
If you need any assistance or have any questions, please get in touch with us via test@cirs-group.com.
Further Information
https://members.wto.org/crnattachments/2022/TBT/EEC/22_7878_00_e.pdf
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