California Proposition 65 (also known as Safe Drinking Water and Toxic Enforcement Act) was enacted as a ballot initiative in November 1986. Prop 65 businesses are required to provide a "clear and reasonable" warning before knowingly and intentionally exposing anyone to a listed chemical “Known to the State” to cause cancer or reproductive harm.

Recently, the Center for Environmental Health (CEH) in the United States has charged over 50 companies for failing to warn about the exposure risks of Bisphenol S (BPS) in paper receipts as required by California Proposition 65. Notices of violation were issued, and there are plans to sue these companies under Proposition 65. According to this law, businesses that fail to comply with the warning requirements may face severe legal consequences, including but not limited to fines and injunctions. If sued and found in violation, companies could face fines in the hundreds of thousands, resulting in significant financial and reputational damage.

In April 2025, New Mexico passed the Per- and Poly-Fluoroalkyl Substances Protection Act, aimed at strengthening the regulation of per- and poly-fluoroalkyl substances (PFAS) to protect human health and the environment.

Cosmetic Export Testing (International) US, EU, ASEAN, Middle East, Canada, Japan, South Korea,

Recently, under the Toxic Substances Control Act (TSCA) and related regulations, the U.S. Environmental Protection Agency (EPA) announced the listing of five chemical substances as high-priority substances for risk assessment. This decision took effect on December 18, 2024.

On November 26, 2024, the U.S. Food and Drug Administration (FDA) proposes to establish and require standardized testing methods for detecting and identifying asbestos in talc-containing cosmetic products, as mandated by the Modernization of Cosmetics Regulation Act of 2022 (MoCRA). This proposed rule, if finalized, would protect consumers by, to the extent it reduces exposure to asbestos, resulting in fewer asbestos-related illnesses.

In December 11, 2024, the U.S. Food and Drug Administration (FDA) issued updated guidance for industry on registration and listing of cosmetic product facilities and products. The guidance finalizes the frequently asked questions and answers (FAQ) in Appendix B (Q1-19). In addition, three new FAQs (Q20-22) in Appendix B of the guidance are marked as “for comment purposes only”. These three FAQs are available for comments before January 13, 2025.

In 2024, CIRS Group helped enterprises successfully apply for various types of International Nomenclature of Cosmetic Ingredients (INCI) names, including peptides, chemical synthesis-based ingredients, and more.

This article compiles the cosmetic regulation updates that took place in September and October in Europe (including the UK), America, and the Asia Pacific region.

The International Agency for Research on Cancer (IARC), part of the World Health Organization (WHO), has updated its classification of talc and acrylonitrile, now labeling it as “probably carcinogenic to humans” (Group 2A) for all forms not containing asbestos or asbestiform fibers. This update, published in The Lancet Oncology, may significantly impact the chemical industry, especially under California’s Proposition 65 (Prop 65).