On 25 July, 2025, the European Commission is set to hold a final vote on amendments to the REACH Regulation administrative fees by 30 August 2025. If passed, the revised regulation will take effect 20 days after publication in the EU Official Journal.

On June 2, 2025, the European Commission officially adopted Regulation (EU) 2025/1090, imposing new restrictions on the use of N,N-dimethylacetamide (DMAC) and 1-ethylpyrrolidin-2-one (NEP).

On April 29, 2025, the European Chemicals Agency (ECHA) announced a proposal to restrict the use of hexavalent chromium (Cr(VI)) substances within the European Union. This measure aims to protect human health and the environment from the carcinogenic risks associated with these substances.

On April 3, 2025, at the CARACAL-54 meeting of the joint advisory body REACH-CLP, the European Commission officially released the final proposal for the reform of the REACH Regulation. The European Chemical Industry Council (Cefic) pointed out that the digital transformation is expected to increase costs for SMEs by 40%, and that the 10-year review cycle and complex mixed assessment models may slow down the development of innovative pharmaceuticals.

To assist enterprises, member state regulatory authorities, and the public in understanding the new rules, the European Commission released the Implementation Guide for the REACH Microplastics Restriction (Annex XVII Entry 78) in April 2025. Developed by ECHA in collaboration with member states, the guide is non-binding but provides detailed instructions for implementing the regulation.

On 1 April 2025, Regulation (EU) 2025/660 was published by the European Commission, amending Annex XVII of the REACH Regulation (EC) No 1907/2006 concerning the Registration, Evaluation, Authorization, and Restriction of Chemicals (EU REACH). The revision specifically addresses polycyclic aromatic hydrocarbons (PAHs) in clay targets used for shooting.

The European Commission revised the Carcinogenic, Mutagenic, or toxic to Reproduction (CMR) substances list within REACH's Annex XVII , introducing three key changes.

In accordance with REACH regulations, before conducting tests under Annex IX and X (for registration volumes of 100-1000 tons per year and over 1000 tons per year), registrants must submit a testing proposal (TP). After a consultation period, ECHA will finalize the testing requirements based on feedback and the characteristics of the substance.

ECHA released the Community Rolling Action Plan (CoRAP) for the years 2024-2026, which updates a list of 28 substances suspected to pose risks to human health and the environment for evaluation by the competent authorities of 11 Member States.