Upcoming Approval for REACH Registration Testing Proposals for 12 Substances
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In accordance with REACH regulations, before conducting tests under Annex IX and X (for registration volumes of 100-1000 tons per year and over 1000 tons per year), registrants must submit a testing proposal (TP). After a consultation period, ECHA will finalize the testing requirements based on feedback and the characteristics of the substance.

On May 14, 2024, the European Chemicals Agency (ECHA) announced 12 new substance testing proposals and invited the public to submit their comments by following dates.

ECHA’s public consultation on substance testing proposals is a transparent process to determine if additional testing is needed for chemical registration dossiers to ensure safety. This process gathers input from various stakeholders to improve chemical safety assessments. After the consultation period, ECHA will adjust the testing requirements based on the feedback. Registrants must then conduct the specified tests, submit the results, and update their safety documentation to ensure safe use and promote industry sustainability.

NameEC Num./ CAS Num.Hazard endpoint for which vertebrate testing was proposedDeadline for submitting information
4,4'-methylenebis[N,N-bis(2,3-epoxypropyl)aniline]

249-204-3

28768-32-3

6.1.2 Long-term toxicity to fish27/05/2024
Dibromomethane

200-824-2

74-95-3

7.6.2 Genetic toxicity in vivo27/05/2024
Diethyl succinate

204-612-0

123-25-1

7.5.1 Repeated dose toxicity: oral

7.8.2 Developmental toxicity / teratogenicity

27/05/2024
Manganate(1-), glycinato-N,O)[sulfato(2-)-O]-, hydrogen

838-538-0

52139-31-8

7.6.2 Genetic toxicity in vivo27/05/2024
Menthol

201-939-0

89-78-1

6.1.2 Long-term toxicity to fish28/06/2024
N,N-dimethylacrylamide

220-237-5 

2680-03-7

7.8.2 Developmental toxicity / teratogenicity28/06/2024
N-(2-(dimethylamino)ethoxy)ethyl)-N-methyl-1,3-propanediamine

470-720-1

189253-72-3

7.5.1 Repeated dose toxicity: oral

7.8.2 Developmental toxicity / teratogenicity

27/05/2024
N-[3-(dimethylamino)propyl] C6-9 alkyl amides

948-134-7

-

6.1.2 Long-term toxicity to fish28/06/2024
Polyhydroxy-N,N-polyalkylbenzene-polycarboxamide

-

-

7.5.1 Repeated dose toxicity: oral

7.8.2 Developmental toxicity / teratogenicity

27/05/2024
Sodium chlorite

231-836-6

7758-19-2

6.1.2 Long-term toxicity to fish

7.6.2 Genetic toxicity in vivo

28/06/2024
Tetramethylammonium hydroxide

200-882-9

75-59-2

7.8.2 Developmental toxicity / teratogenicity||Note: testing proposed with Tetramethyl ammonium chloride (EC no. 200-880-8)28/06/2024
Triisobutyl phosphate

204-798-3

126-71-6

6.1.2 Long-term toxicity to fish27/05/2024

If you need any assistance or have any questions, please get in touch with us via test@cirs-group.com.

Further Information

ECHA 1
ECHA 2